For some graduate students, January means a long slog through cold, gray days and seemingly endless hours in the lab or the library.For the hundreds of students in Harvard’s Graduate School of Arts and Sciences (GSAS), however, January offered a chance to let their hair down and explore topics they might otherwise never contemplate, from questions of race in director Quentin Tarantino’s films to the production of nano-materials to fabricating a hand-crank generator.Those sessions and more were just some of the more than 100 classes, seminars, and workshops that were offered to GSAS students throughout the month as part of the fourth [email protected] The annual January offerings are designed to give students a chance for professional development and social interaction, as well as an opportunity they might not otherwise get during the semester to explore unusual interests.Jason Silverstein (left) listens as GSAS student Andre Green asks a question. Photo by Stephanie Mitchell/Harvard Staff PhotographerFor Andre Green, a fifth-year graduate student in molecular and cellular biology, the “Race, Racism, and Quentin Tarantino” class offered valuable insight into questions of racist writing and writing racism, in addition to a welcome break from the lab.“This is an interesting diversion from lab life,” he said. “One thing I’ve taken away from this is the idea of where Tarantino is coming from as an artist. He’s not trying to make a documentary. Rather, the films are his own interpretation of some historical event. It’s interesting to understand the freedoms he has in making those interpretations, and how he presents them in his films, including ‘Django Unchained.’”The benefits of the [email protected] offerings weren’t limited to the intellectual, though. Jason Silverstein, a Ph.D. student in anthropology, led the Tarantino talk, and said it was the interdisciplinary nature of the classes — which often brought together students from wildly different fields — that attracted him.“That, to me, is the coolest thing about this. It’s a true interdisciplinary program,” Silverstein said. “This is one of those rare times when we can truly have this. It’s exciting to bring together a group of people who might not normally have these conversations.”Discussions about subtext in film, however, barely scratched the surface of this year’s offerings.Along with workshops aimed at reinforcing students’ research skills and the use of quantitative analysis techniques and reference tools, the GSAS partnered with the Office of Career Services to highlight professional development programs, including sessions on making the transition to a non-academic career, expanding professional networks using online social media tools, and navigating the academic job search. The sessions included advice from former students.“Our intention with [email protected] is to give graduate students — who often remain on campus during winter break — an opportunity to stretch themselves intellectually, meet their peers in the Harvard community, and hopefully have some fun,” said Garth McCavana, GSAS dean for student affairs. “The January session also gives us a chance to offer students important professional development opportunities that may be difficult to fit into their busy schedules during the semester.”For female scientists navigating grad school and the launch of professional or academic careers, the Office of Career Services and Harvard Graduate Women in Science and Engineering co-sponsored a seminar titled “Empowering Women in the Job Search.” Led by Heather Law, assistant director of career services, the session addressed everything from common interview mistakes to advice on networking after the job is landed.For female scientists navigating grad school and the launch of professional or academic careers, the Office of Career Services and Harvard Graduate Women in Science and Engineering co-sponsored a seminar led by Heather Law, assistant director of career services. Photo by Jon Chase/Harvard Staff Photographer“The statistics are clear. New female college graduates are earning 17 percent less than their male counterparts. And among full-time workers in the population as a whole, women still only early 77 cents for every dollar their male counterparts make,” Law said. “In addition, women report salary expectation of between 3 and 30 percent lower than men for the same jobs. That’s a drastic difference. That means men are going in and negotiating at much higher rates, and asking for much more money than women are. There is a big discrepancy, and that’s something I want you to be aware of so when you’re in that situation, you’re going to be able to advocate for yourself in the way you should.”Too often, Law said, women can fall victim to the “imposter syndrome,” believing their careers are due more to luck than expertise, or they may deflect credit away from themselves and toward others, with the result being lower career self-esteem.“What effect does that have on your job search or your ability to take part in a job?” Law asked. “In fact, it actually has a lot to do with it. It results in you feeling doubtful about your abilities. It results in you potentially spending a lot of time focusing on the mistakes you make rather than the positives. You may miss out on opportunities for advancement. It really can affect either your job search or your career.”“I think it’s a great opportunity for women to come together and talk about any shortcomings they feel they may have,” said Shanying Cui, co-chair of Harvard Graduate Women in Science and Engineering, following the seminar. “We had identified negotiation as a weakness that many people have, so we thought that would be an excellent starting point for this discussion.”
Coordinating against malaria Collins’ group at the Wyss Institute and MIT co-developed the SHERLOCK technology with Feng Zhang’s group at the Broad Institute. It was licensed to Sherlock Biosciences, a startup that used it to create a rapid molecular diagnostic for other disease applications, and recently received an emergency use authorization from the FDA for its COVID-19 rapid diagnostic.Other methods have been developed that, like the new SHERLOCK assay, amplify and detect the DNA (or RNA) nucleic acid material of Plasmodium species. However, to date, these methods remain limited by their need for expensive laboratory equipment.“Importantly, the assay is compatible with different sample types, such as whole blood, plasma, serum, and dried blood, and all components required for amplification, Cas12a activation and signal generation can be lyophilized in a single test tube to work together in a one-pot-reaction after they are reconstituted and mixed with patient sample,” said first-author Rose Lee, a clinical fellow in Collins’ group and Boston Children’s Hospital. “This … allows testing to be performed in low-resource settings with minimal expertise.”Adapted from a Wyss Institute online article. Faith-based approach in battling malaria Related In ongoing efforts to eradicate malaria, an ultrasensitive test that offers rapid, species-specific diagnostic capabilities has been developed by a research collaboration led by James Collins, a core faculty member at Harvard’s Wyss Institute for Biologically Inspired Engineering.To achieve the goal set by the World Health Organization’s (WHO) Global Malaria Control Programme, all local transmission of malaria parasites in defined geographic areas must be eliminated. Developing tests that are useful in the low-resource settings of many areas with endemic malaria is key.Currently, the presence of the four major malaria-causing Plasmodium species P. falciparum, P. vivax, P. ovale, and P. malariae is determined by microscopic analysis of blood samples in which parasites can be detected in red blood cells, or with so-called rapid diagnostic tests for specific Plasmodium proteins (antigens).“Unfortunately, available rapid diagnostic approaches cannot distinguish all four Plasmodium species from one other, which can be important to initiate the definitive course of treatment,” said Nira Pollock, associate medical director of Boston Children’s Hospital’s Infectious Diseases Diagnostic Laboratory and associate professor of pathology and medicine at Harvard Medical School (HMS). “And, most importantly, they are ineffective for detecting low numbers of Plasmodium parasites in asymptomatic individuals.”“These ‘asymptomatic carriers’ are silent reservoirs for ongoing transmission by malaria-spreading mosquitoes and extremely important for ongoing global efforts to eradicate malaria,” added Jeffrey Dvorin, associate professor of pediatrics at HMS and senior associate physician in infectious diseases at Boston Children’s Hospital.The research team, assembled by clinical fellow Rose Lee and included Pollock and Dvorin, created a field-applicable, ultrasensitive diagnostic assay that specifically detects DNA sequences from all Plasmodium species in symptomatic and asymptomatic malaria. The new method combines an optimized 10-minute rapid sample preparation protocol with the CRISPR-based SHERLOCK system to enable highly specific and sensitive Plasmodium detection in another 60 minutes in simple reporter devices. It is published in PNAS.,“This field-ready SHERLOCK diagnostic malaria assay surpasses the sensitivity and specificity requirements set by the WHO for a desired test that can be used to detect low parasite density in asymptomatic carriers of all major Plasmodium species,” said Collins. “Its highly streamlined design could provide a viable solution to the present diagnostic bottleneck on the path to eliminate malaria, and more generally enabling malaria surveillance in low-resource settings.”Collins is a lead of the Wyss Institute’s Living Cellular Devices Focus Area, and also the Termeer Professor of Medical Engineering & Science at MIT.Team members demonstrated their engineered SHERLOCK (specific high-sensitivity enzymatic reporter unLOCKing) assay to be capable of detecting less than two parasites per microliter of blood, the WHO’s suggested “limit of detection” (LOD) for a test with broad utility in endemic areas. Showing the assay’s clinical potential by analyzing clinical samples containing P. falciparum and P. vivax species, they called out them out with 100 percent sensitivity, by correctly identifying true positive samples, and 100 percent specificity, by also correctly identifying samples lacking a certain Plasmodium species in true negative samples.Near 100 percent sensitivity and specificity are key attributes of diagnostic assays to be used in real-world testing. Moreover, the assay is designed so that it can also determine the presence of frequently mutated P. falciparum strains that have lost their HRP2 antigen and thus escape the detection by common rapid diagnostic tests. Seeking new momentum in malaria fight As cases increase in Africa, medical and religious communities join forces Progress will be lost if new president abandons fight Leaders in eradication efforts gather at Harvard to trade ideas, experiences Global leaders converge at Harvard, pointing toward long-term eradication as well as short-term reduction Politics biggest threat to malaria effort
Have you ever thought about the smallest particles of matter and how they can be used to create good?Notre Dame’s Center for Nano Science and Technology, better known as NDnano, has been working since 2001 to answer this and other unsolved scientific questions using nanotechnology — the branch of technology that studies and manipulates extremely small matter such as atoms and molecules at a ‘nanoscale’ length.NDnano is a collection of faculty members who are interested in what can be learned by understanding the nanoscale. At the group’s meetings, engineers and scientists across the University gather to share their understanding of the scale with each other and to solve nanoscience problems.“It’s really quite exciting when you start to think about how the world works on an atomic scale,” Alan Seabaugh, the director of NDnano, said. “There are many abilities that have come out in the last couple decades about this topic. These abilities are starting to give us great insight into how we can engineer new kinds of structures so we can revisit problems that have solutions now, but were solved before we had this level of understanding.”Recent work at NDnano has included continuing to invest in the future of computing, Seabaugh said. Notre Dame recently won a research center in an effort led by Suman Datta, the Freimann chair of engineering. Called “Ascent,” the center is looking at the bottlenecks of computing and how they can be solved.“This center has been a big win for the University,” Seabaugh said. “It’s a national center that’s come from NDnano that has several other universities involved and well over 100 researchers in that institute.”Other projects include research into drug delivery to cancer cells, new fuels, nuclear sustainability, solar and thermal electrics and analyzing water for pathogens, he said.NDnano aims to engage students, too — a number of undergraduate research fellowships are offered during the summer to propel students into projects with the center. Additionally, Seabaugh said faculty research groups often have openings for undergraduates.Even with the progression of NDnano’s research, however, the organization’s goal remains the same — to address questions with an aim to promote the greater good.Ever since they began meeting during lunch back in 2001, the NDNano faculty continues meeting monthly to discuss the nanotechnology topics and questions that interest them. After comparing ideas, they aim to write winning proposals. “We talk about problems we’re interested in addressing, we talk about things that we can do and can’t do, and it’s the faculty teaching the faculty and collaborating on problems that we want to tackle together,” Seabaugh said.Tags: Alan Seabaugh, Ascent, nanoscale, nanotechnology, NDnano
First of all, Revelton Suites is one of the brands that belongs to the international Revelton Hotels & Apartments chain. Revelton Suites are distinguished by spacious suites and classic pastel-colored design. These are usually small mansions with a limited number of apartments, which ensures the guests’ privacy.Revelton has been using a contactless check-in system for about 1 ½ years, with all guests registering online and entering their apartments using a PIN-code. Waiting in line at the reception is long gone, and all employees work remotely. Despite this system, the staff manages to cater to the guests’ needs with attention and care using popular instant messengers. At every point in the stay, the guest receives tips and advice from the locals. Revelton calls this great feature Online Reception.This operation model turned out to be very valuable, given the current situation in the world. With the advent of Covid-19, Revelton has added essential amenities such as antiseptic in the lobby, disposable masks and disinfectant wipes for each guest. When you arrive at this chain’s apart-hotels, you can be sure of your safety.- Advertisement – OlderBreaking Travel News investigates: Is the Covid-19 vaccine a silver bullet for travel? – Advertisement – Revelton Hotels & Apartments have an average 9.6 rating on Booking.com, and are at the top of the list on Tripadvisor. In addition, Revelton Suites Tallinn has received the Best of the Best award from Tripadvisor this year and has been recognized as one of the best in Europe. In addition, the apartments may even be slightly better equipped than home: projectors linked to Apple TV, free Netflix, fully equipped kitchens and a great selection of books: you simply won’t feel like leaving!Natalia Pugacheva, Managing Director of Revelton Suites Tallinn: “We receive a lot of grateful reviews, which praise our contactless check-in system. In addition, we have created a special site for our guests with city recommendations, as well as instructions for everything that our apartments offer: from the projector to the coffee maker. This way, our guests always feel our attention and remain delighted with their stay.”Revelton’s experience demonstrates that it’s possible to continue to evolve and become leaders in the hospitality industry – even during a pandemic.- Advertisement – Every year since 1993, the best hotels, tour operators, airlines and travel industry-related businesses take part in the World Travel Awards and compete for the right to receive the coveted prize.This year, Revelton Suites, located in Tallinn (Estonia) and Karlovy Vary (Czech Republic), once again won the Leading Serviced Apartments category in their respective countries. This is the third trophy for the apart-hotel in Tallinn, and the fourth for the one in Karlovy Vary. How do they do it?- Advertisement –
May 14, 2007 (CIDRAP News) – The dispute over the sharing of H5N1 avian influenza samples was high on the agenda as the annual meeting of World Health Organization (WHO) member countries began today in Geneva.Indonesia has been withholding H5N1 virus samples since the start of this year out of fear that drug companies would use them to make vaccines priced beyond the country’s reach. WHO officials hope to solve the problem by the time the 60th World Health Assembly (WHA) ends on May 23.”We hope that it [the standoff] will be fully resolved during the assembly,” WHO spokesman Iain Simpson told Agence France-Presse (AFP), according to a story published yesterday.The 193 WHO members will also consider whether remaining smallpox virus stocks should be destroyed, launch a massive yellow fever vaccination campaign in Africa, bolster polio eradication efforts, and examine the effect of climate change on health, according to WHO documents and news agencies.The United States’ top health official weighed in on the virus-sharing dispute today, urging all countries to share samples without attaching strings, according to an AFP report today.”We continue to call on countries everywhere to share influenza samples openly and rapidly, without preconditions,” US Health and Human Services Secretary Mike Leavitt was quoted as saying.The WHO has coordinated the international sharing of flu virus samples by national and WHO collaborating laboratories for more than 50 years. Samples of both seasonal flu viruses and novel strains like H5N1 are used to monitor viral evolution and drug resistance and to develop vaccines.After a meeting in late March, Indonesian officials said they would resume sharing the virus samples immediately, in return for a WHO promise to revamp its sample-sharing rules.But Indonesia has continued to withhold the samples, saying it wants a written guarantee that they won’t be shared with drug companies without the country’s consent.According to yesterday’s AFP report, a senior Indonesian health official said the country would urge WHO members at the meeting to scrap the existing policy on sharing of samples.A WHO staff (Secretariat) report prepared for the WHA outlines “best practices” for sharing of flu virus samples, as approved by the WHO’s Pandemic Influenza Task Force at a meeting last September. The report:Calls on member countries to continue sending flu virus specimens to the WHOSays WHO collaborating and reference labs should provide flu virus samples to vaccine producers for the “sole purpose” of developing safe and effective vaccinesEncourages vaccine producers “to expand production and/or transfer technology in order to increase the supply and availability of influenza vaccines globally”Says WHO collaborating labs should not use virus samples for purposes other than public health risk assessment and vaccine development without permission from the source countrySays neither WHO collaborating centers nor national labs should sell virus specimens or otherwise try to profit from participating in the WHO’s surveillance networkUrges WHO collaborating centers and national labs not to impose “agreements or administrative procedures” that would inhibit WHO flu surveillanceUrges member countries that have flu vaccine supplies and access to other flu protection technologies to make “specific efforts” to share these benefits with countries that lack themIn other business at the WHO meeting, Director-General Margaret Chan will ask members to approve a 15% increase in the agency’s budget for 2008-09, to $4.2 billion, according to AFP.The meeting is also scheduled to officially launch a 4-year campaign to vaccinate 48 million people in 12 African countries against yellow fever, the story said. The WHO estimates that yellow fever attacks 200,000 people in Africa and Latin America each year and kills 30,000, AFP reported.See also:WHA journal with schedulehttp://www.who.int/gb/ebwha/pdf_files/WHA60/A60_J-en.pdfReport by the WHO Secretariat on “Avian and pandemic influenza: Best practice for sharing influenza viruses and sequence data”http://www.who.int/gb/ebwha/pdf_files/WHA60/A60_ID1-en.pdfWHO staff report on destruction of smallpox virus stockshttp://www.who.int/gb/ebwha/pdf_files/WHA60/A60_ID1-en.pdfReport of the eighth meeting of the WHO Advisory Committee on Variola Virus Researchhttp://www.who.int/gb/ebwha/pdf_files/WHA60/A60_40-en.pdf
High increase in tourist arrivals and overnight stays in the first six monthsIn the first six months of 2017, in commercial accommodation facilities, tourists realized 5 428 thousand arrivals and 20 358 thousand overnight stays, which is an increase in tourist arrivals by 23% and an increase in tourist nights by 23% compared to the same period in 2016.Out of the total number of tourist arrivals and overnight stays, foreign tourists realized 4 thousand arrivals and 624 thousand overnight stays, which is an increase of 18% in arrivals and a 335% increase in overnight stays. Most overnight stays of foreign tourists were realized by tourists from Germany (25%), Austria (25%), Slovenia (26%) and Great Britain (11%). In the period from January to June 9, domestic tourists also realized 7% more arrivals and 2017% more overnight stays than in the same period last year. According to the Central Bureau of Statistics (CBS), 2 tourists came to commercial accommodation facilities in June, which is 526% more than in June 33.Tourists realized 12 030 thousand tourist nights: 6% by domestic tourists and 94% by foreign tourists. Compared to June 2016, tourists realized 35% more overnight stays. Domestic tourists came 16% more and realized 14% more overnight stays, while foreign tourists came 35% more and realized 36% more overnight stays in June 2017 than in the same period last year. The highest number of overnight stays of foreign tourists in June 2017 was realized by tourists from Germany (29%), Austria (10%) and Slovenia (8%). They are followed by tourists from Poland and the Czech Republic (both 7%), the United Kingdom (6%) and Italy (5%).Rovinj is the first in terms of the number of overnight staysRovinj realized the highest number of tourist nights in June 2017, 613 thousand overnight stays. The highest number of overnight stays was realized in the group Camps and camping sites, 53%, followed by the group Hotels and similar accommodation, 26%. Most overnight stays were realized by tourists from Germany, 41%, who realized on average 9 nights per arrival, and tourists from Austria, 17%, with an average of 5 nights per arrival.Most nights spent in rooms for rent, apartments, studio apartments and holiday homesIn June 2017, most overnight stays were realized in rental rooms, apartments, studio apartments and holiday homes, 4 thousand overnight stays, which is 866% of the total number of overnight stays. Compared to the same period last year, the number of arrivals in these types of accommodation increased by 40% and the number of overnight stays by 49%.In June 2017, tourists were offered 336 thousand rooms, suites and camping places with a total of 883 thousand permanent beds. In the group Hotels and similar accommodation, a total of 78 thousand rooms and suites with a total of 161 thousand permanent beds were available to tourists. The average occupancy of rooms was 75%, and permanent beds 78%. In June, the highest number of overnight stays was realized by tourists under 14 years of age, 2 thousand overnight stays, which is 051% of the total number of overnight staysSource: CBS
Unit oversupply has reduced rents and is tipped to slow down the number of first home buyers hitting the market.CHEAPER rents as a result of unit market oversupply are tipped to slow down the move of first home buyers into ownership.The latest BIS Oxford Economics Outlook for Residential Land said the oversupply in the Brisbane apartment market will have flow on effects in the house and land market as well.Senior manager Angie Zigomanis said falling unit prices would shift buyer demand from the house market to the unit market.More from news02:37Purchasers snap up every residence in the $40 million Siarn Palm Beach North1 hour agoNew apartments released at idyllic retirement community Samford Grove Presented by A national slow down in rent increases could also mean first home buyers stay put in the rental market longer and save a more substantial deposit.The slow down in buyers for houses meant production of land would start to drop off.The report forecasts some continued moderate growth in land production to the end for this financial year, but that it will ease off after that.It also predicted the production would be in areas outside of the Brisbane City Council region.“Diminishing land opportunities within Brisbane city will see the development rent increasingly moving to outer Brisbane regions.It said Brisbane and Gold Coast markets had experienced a moderate upturn in production of new housing since 2013.
Loading… Promoted ContentThese Films Were Sued For The Weirdest Reasons8 Superfoods For Growing Hair Back And Stimulating Its GrowthWhich Country Is The Most Romantic In The World?6 Ridiculous Health Myths That Are Actually True7 Reasons It’s Better To Be A VeganRevealed: 6 Hidden Secrets Of The Great Wall Of ChinaWhat Happens To Your Brain When You Play Too Much Video Games?7 Worst Things To Do To Your PhoneTop 7 Best Car Manufacturers Of All Time9 Iconic Roles That Could Have Been Played By Different Actors7 Black Hole Facts That Will Change Your View Of The Universe7 Ways To Understand Your Girlfriend Better Fortuna Dusseldorf are sending Zak Steffen back to Manchester City. Nov 4, 2018; Columbus, OH, USA; Columbus Crew SC goalkeeper Zack Steffen (23) in the second half against the New York Red Bulls at Mapfre Stadium. Mandatory Credit: Trevor Ruszkowski-USA TODAY Sports Steffen will return to City for tests on a persistent knee problem he has been suffering at Fortuna Dusseldorf. Steffen has not played in five games in 2020, but has 18 appearances all season.Advertisement A Fortuna statement said: “Goalkeeper Zack Steffen will undergo medical examinations over the next few days due to his persistent knee problems, which are organized by his home club Manchester City. “Fortuna’s physiotherapist Lucas Trittel, who is involved in all processes as part of the medical department, will accompany Steffen to act as a contact person. Read Also:Bundesliga: Ex-Man City striker takes over at strugglers Fortuna “Both clubs are in constant communication: Fortuna’s sports director Lutz Pfannenstiel and Manchester’s sports director Txiki Begiristain have agreed on this procedure in close consultation with the medical departments of both clubs.” FacebookTwitterWhatsAppEmail分享
MILROY, Ind. — The Milroy Economic Development Corporation and the Rush County Sheriff’s Department will hold a town hall meeting regarding the intersection of State Road 3 and State Road 244 tomorrow.The meeting will be held at the Milroy United Methodist Church beginning at 6:30.A three-year study administered by the Rush County Sheriff’s Department found that 16 accidents were reported, of which 15 had injuries, at that intersection.State officials have also noticed the number of accidents and are working to make improvements to reduce the number of accidents.