If Wisconsin and Purdue drafted the blueprint for defeating the No. 1 Buckeyes, Kentucky didn’t follow it. The Buckeyes were riding a nearly flawless season into the NCAA Tournament, aside from two losses against teams propelled to victory by peak performances from their top players. OSU had the second-best start to a season in program history, with 24 straight wins, only behind the 1960–61 team’s 27, and it tied its second-best record for wins in a season, with 34. The team won both the regular-season and conference titles, earning the overall No. 1 seed in the NCAA Tournament. Then, No. 4 seed Kentucky stopped OSU in its tracks. When the Wildcats ended OSU’s national title run with a 62-60 victory on Friday, they used a collective effort on defense to prevent the Buckeyes from running away with the game, as OSU had in the second and third rounds. “Nobody talks about (Kentucky’s) defense,” OSU coach Thad Matta said, following his team’s loss to Kentucky on Friday. “And, you know, obviously they’re very effective defensively.” The Wildcats held OSU to a dismal 32.8 percent shooting, the team’s third-worst shooting performance of the season, next to its 32.2 percent shooting against Florida State on Nov. 30 and Northwestern on March 11. Despite having its worst shooting percentage of the season in those two contests, OSU still pulled off wins. “Some of the shots we missed are shots we have been making all year,” OSU guard Jon Diebler said Friday. “Tonight they weren’t going in.” Kentucky totaled 11 blocks against OSU, which is the most any team has achieved against the Buckeyes in a tournament game. Forward Josh Harrellson led Kentucky with 17 points, 10 rebounds and three blocks. Teammate DeAndre Liggins also swatted away three shots. “I think Harrellson is probably the most underrated player in college basketball,” Matta said. “He’s a tremendous player and knows his role and does it well.” The Wildcats’ defense held the Buckeyes to 38 fewer points than they totaled in their previous game against George Mason. It also allowed the Buckeyes to shoot just 37.5 percent from 3-point territory, down from 61.5 percent against the Patriots. “I thought they did a good job of challenging shots, obviously, with their length,” Diebler said. “We are going against length all year and those are shots that we make, and tonight they weren’t going in.” Coming off a 7-for-7 shooting performance from deep against George Mason, OSU’s David Lighty shot just 1-of-4 against Kentucky. “They flew at shooters,” Lighty said Friday. “I mean, they crowded the paint. They did a good job of that.” The Buckeyes also struggled to draw fouls against Kentucky in the second half. After drawing two fouls against each of five Wildcats in the first half, resulting in 12 points from free throws, OSU gained only four points from the charity stripe in the second half. “The tide turned in the second half,” Matta said. “They were doing a pretty good job of switching their matchups and getting guys in and out of the game that were in foul trouble.” Each of the Buckeyes’ regular-season losses, however, could be attributed to a standout performance from a single opposing player. In OSU’s first loss, Feb. 12 at Wisconsin, the Buckeyes blew a 15-point lead with 13 minutes to play, mostly because of a clutch performance by Badgers guard Jordan Taylor. In the game’s final 13 minutes, Taylor scored 21 points on 6-of-7 shooting, and assisted on four of his team’s other six field goals, thrusting the Badgers to a 71-67 win against the Buckeyes. Overall, he tallied a game-high 27 points on 8-for-13 shooting, including 5-of-8 from beyond the arc, and also made a game-high seven assists. E’Twaun Moore led Purdue to a 76-63 home victory against the Buckeyes on Feb. 20, scoring a career-high 38 points on 13-for-18 shooting, including 7-of-10 from deep. “Those were two, when you think about it, maybe two of the best performances in college basketball this year,” Matta said. “As my luck always has it, I get a first-row seat to watch it.” But, as Kentucky proved on Friday with its 45.8 percent shooting, a team doesn’t have to have one of the “best performances in college basketball” to defeat the No. 1 team.
Social relationships including family and friends play a key role in an individual’s recovery from substance-abuse problems and at the same time may also negatively influence them to become an addict, finds a study. The findings showed that the links between substance use and social connections are bi-directional and strong.“Our data show that social mechanisms substantially affect clinical outcomes over long periods of time,” said Robert L Stout, a scientist at the Pacific Institute for Research and Evaluation, a US based non-profit organisation. Also Read – ‘Playing Jojo was emotionally exhausting’ Often after treatment for substance abuse problems, clinicians urge patients to avoid ‘bad’ social contacts and foster ‘good’ ones, the study said.“How clients change their social connections after treatment is a strong indicator of substance abuse outcomes one year and three years later,” Stout added. Nearly 20 per cent of relationship terminations pose a relapse risk to the patients. On the other hand around 10 per cent of relationship terminations occur because of the patients’ continued use of substances. Also Read – Leslie doing new comedy special with NetflixFamily and partner relationships are the least likely to end, but about half of friendships seem to end over the span of two years.Substance abuse strongly affects families and friends of alcohol abusers, accounting for much of the harm due to alcohol abuse, said the paper that underlines the importance of investigating how we can address social mechanisms in treatment to improve outcomes. “Alcohol problems involve biological, psychological and social aspects. Therefore, intervening in the social connections of alcohol abusers may help to mitigate the damage done by alcohol misuse,” Stout suggested. The team followed patients’ undergoing treatment for drugs and alcohol for two years to examine how changes in new and old relationships are linked to substance abuse. They focussed on factors associated with relationship break ups, observing how different types of relationships affect and are affected by substance use. The researchers also looked at how relationship changes ultimately affected treatment outcomes.The results were presented at the 39th Annual Research Society on Alcoholism in New Orleans, recently.
Source:https://www.plos.org/ Reviewed by James Ives, M.Psych. (Editor)Dec 14 2018Researchers have developed genetically modified pigs that are protected from classical swine fever virus (CSFV), according to a study published December 13 in the open-access journal PLOS Pathogens by Hongsheng Ouyang of Jilin University, and colleagues. As noted by the authors, these pigs offer potential benefits over commercial vaccination and could reduce economic losses related to classical swine fever.CSFV is responsible for a highly contagious, often fatal disease that causes significant economic losses. Due to the economic importance of this virus to the pig industry, the biology of CSFV has been investigated extensively. Despite efforts by many government authorities to stamp out the disease from pig populations, it remains widespread, and it is only a matter of time before the virus is reintroduced and the next round of disease outbreaks occurs. There is an urgent need to develop effective approaches to eradicate CSFV. To address this challenge, Ouyang and colleagues generated CSFV-resistant pigs by combining a gene-editing tool called CRISPR/Cas9 with RNA interference (RNAi), a technique that silences gene expression.Related StoriesStudy reveals how dengue virus replicates in infected cellsCommon cold virus strain could be a breakthrough in bladder cancer treatmentVirus killing protein could be the real antiviral hero finds studyThe researchers demonstrated that these pigs could effectively limit the replication of CSFV and reduce CSFV-associated clinical signs and mortality. Moreover, disease resistance could be stably transmitted to first-generation offspring. Currently, the researchers are conducting long-term studies to monitor the safety and effectiveness of this approach as these animals age. According to the authors, generating anti-CSFV pigs using a genome editing-based strategy could be a direct and effective approach to facilitate the permanent introduction of novel disease resistance traits into the mass population of production pigs via conventional breeding techniques. In addition, this antiviral strategy can be applied to other domestic species and could provide insights for future antiviral research.Ouyang adds, “These tansgenic pigs could effectively limit the replication of CSFV and reduce CSFV-associated clinical signs and mortality.”